That's what I do. With plenty of water or whatever. It's just quicker and easier and you don't have to worry about it's stabibility in solution or the fact that it won't dissolve and starts to settle to the bottom.

In a PWO shake that's the best way if you have a shake with a liter or more of water. Same with your creatine. I only drink half the shake all at once and then I drink the rest of it slowly, so I spoon my glutamine and creatine into my mouth at the beginning. If I were to mix it in the shake it would be hanging around in solution too long and I would have to chug over a liter of liquid so I wouldn't have to worry about it breaking down.

But if I chugged the whole shake at once that would be counterproductive because I'm putting too much in my stomach at once so it will take more time for the protein and sugars to get into my system.

The only thing is that if you use a micronized product - be careful - that stuff is so fine it will hit your throat a choke you. You could end up coughing up a big cloud of powder.