i agree with DrX. 25mg/day for the first 4 wks will be plenty.

as for the pins... that 22 would not be my first choice. heres what i would use:

draw: 19g or 20g (the smaller the diameter the less you'll tear up the stopper, but the longer it'll take to draw)

pinning
delts: 25gx5/8' buried
glutes/quads: 25gx1.5'

i've never shot with a 22, 23 is the largest bore i've hit with and it is a harpoon compared to the 25s.