It doesn't matter, but I recommend you just take it everyday unless it's a special blend. After the loading phase and regular use, your muscles are completely saturated. It'll take a month of non use before your muscles are completely sapped of the supplemented creatine. So....If you have regular creatine mono, just take it everyday. On non training days, I'd take one of those servings as soon as you wake up. If it's some special expensive blend, such as Xpand, just take it pre and post. I also want to point out if it's something like Noxplode, just take it preworkout only.
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