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Old 08-17-2005, 05:17 PM
Darkhorse Darkhorse is offline
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Default Hypertrophy-specific.com

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The DOMS that is felt the day after, or even not until 2 days after, is most likely a result of an inflammatory response. Prostaglandins are released in the tissue which hyper-sensitize the nerves. This is not the only reason but most research seems to agree that this is the most likely mechanism.

Microtrauma can occur with or without this type of soreness. At the same time, a certain degree of growth can also occur with or without microtrauma depending on how you define microtrauma. It isn't necessary to have major microtrauma. We only need to disrupt the membranes enough to get satellite cells activated and fusing with existing fibers. Without this step, the fiber may enlarge slightly, but it cannot grow significantly because of a fixed nuclear to sarcoplasmic ratio. Unless new nuclei are added from satellite cells, the volume of the fiber will not increase beyond rather small increments.

So my point is that although DOMS, microtrauma, and hypertrophy are all related, they are not entirely dependant on one another.

However, a low level of DOMS is a good indicator of what kind of stimulus you created for the tissue and usually indicates that you are in the process of growth if you can maintain an adequate stimulus over time. I like to be a little sore thorughout the entire cycle. When my training is too infrequent and/or my increments are too small, the soreness usually goes away and gains "seem" (this is subjective) to be slower. Then again, I have made good gains at times with little or no soreness...

- Bryan Haycock
The first paragraph is an scientific explanation for your delayed muscle soreness. The rest is just bonus points. If anyone needs to look for actual scientific research, there's one of two places I always look to:
1. Pub Med journals
2. Hypertrophy-Specific

Just FYI-
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